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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

B. Walker

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2 papers indexed here

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Open access Sep 2026

Innate immune imprints shape HIV-1 reservoir cell persistence during long-term antiretroviral therapy

Host immune responses that can target and eliminate HIV-1 reservoir cells during suppressive antiretroviral therapy are poorly understood. Here, analyzing over 6,000 proviral DNA amplicons from 104 individuals on long-term antiretroviral therapy, we found that carriers of HLA-C2 allotypes, which promote NK cell educati...

Toong Seng Tan, Wei-Wei Sun, Ce Gao et al. · 2 citations
Open access Aug 2026

Immune control of HIV viraemia in early paediatric infection is associated with induction of HIV-specific CD8+ T-cell activity following multiple treatment interruptions.

BACKGROUND Virus-specific CD8+ T-cells play an important part in HIV cure/remission in adults, yet their role in paediatric immune control is limited by tolerogenic early-life immunity. Very-early ART initiation, while effective in restricting viral reservoir size, also prevents antigenic exposure and, thereby, the ind...

Julia E. Edgar, H. R. Parker, C. Thobakgale et al. · 0 citations

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