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Author

B. Westhus

2 papers indexed here

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Open access Sep 2026

Development and evaluation of machine learning-based prediction-modelling for initial vancomycin serum concentrations in septic ICU patients using clinical health record data

Sepsis remains a life-threatening condition with highly heterogeneous and dynamic pathophysiology, limiting the effectiveness of uniform therapeutic strategies. Beyond timely source control, antimicrobial therapy represents the only causal treatment option. Vancomycin is widely used for treatment of Gram-positive infec...

Robin Grugel, B. Westhus, H. Nowak et al. · 0 citations
Open access Sep 2026

Confounder-Adjusted Plasma Proteomics Identify Robust Protein Signatures in Sepsis Across Two Independent Perioperative Control Cohorts

Background Sepsis is the primary driver of mortality in intensive care. Personalized medicine requires an accurate understanding of the syndrome, and plasma proteomics is increasingly used to characterize its molecular alterations. Comorbidities, demographics and postoperative sterile inflammation complicate this task,...

M. Weber, A. Witowski, M. Bayer et al. · 0 citations

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