Bai-Cheng Zhang

SynOmega: Simplifying Retrosynthesis for Efficient Synthesizability Scoring

Retrosynthesis-based synthesizability scoring triages molecules from generative design but is expensive: every score requires a multi-step search. We present SynOmega, an open-source toolkit that couples a single-step template model, an AND–OR route search, and a route-based synthesizability score (SynScore). Its sin...