Bio-hybrid Nanostructures Orchestrate Photodynamic Remodeling of the Fusobacterium nucleatum-Associated Colorectal Tumor Niche.
The intratumoral microbiota acts as a microbial immune checkpoint in colorectal cancer (CRC), yet current strategies either kill silently without immune activation or permit bacterial rebound through incomplete targeting. Here we report a bio-hybrid assembly designed to synchronize the eradication of CRC cells and thei...