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Bailey T. Chalmers

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Open access Jul 2026

Crosstalk Between Donor T Cells and Recipient IL-33+ Target Tissue Stroma Controls Alloimmune Responses Causing Graft-versus-Host Disease 2260079

Graft-versus-host disease (GVHD) remains a major complication of allogeneic hematopoietic cell transplantation (AlloHCT) and mechanisms releasing IL-33 from nuclear sequestration remain elusive, but free IL-33 directly activates donor CD4+ T cells to promote Th1 differentiation and expansion.

G. Dwyer, L. Mathews, Bailey T. Chalmers et al. · 0 citations

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