CAR T-Cell Therapy in Systemic Lupus Erythematosus: Mechanistic Rationale, Early Clinical Experience, and Future Challenges
Systemic lupus erythematosus (SLE) remains a challenging multisystem autoimmune disease characterised by relapses and remissions, often necessitating lifelong immunosuppression. Over the past decades, the therapeutic landscape has evolved from broad-spectrum agents such as cyclophosphamide to more targeted biologics in...