Review
Open access
Oct 2026
Recent advances in cancer-associated fibroblasts in colorectal cancer: functional subtypes, spatiotemporal dynamics and therapeutic targets.
Colorectal cancer (CRC) is a malignant tumour with an extremely high global incidence rate; its development and progression are closely linked to fibroblasts within the tumour microenvironment (TME). In recent years, single-cell and spatial multi-omics technologies have revealed the high heterogeneity of fibroblasts in...
Yuang Ding, Shao-Hui Zhang, Yan-Feng Guo et al.
· Neoplasia · 0 citations