Author

Bao-Feng Wang

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Open access Sep 2026

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

ABSTRACT Radiotherapy is a major treatment for meningioma, but radioresistance remains a key obstacle to durable disease control. Here, we show that escape from therapy‐induced senescence (TIS) is a hallmark of radioresistant meningioma cells and identify a novel glycolysis‐H3K27 lactylation‐PROS1‐TYRO3‐CARF axis under...

Zhuo-Hang Wang, Qi-Xiang Zhang, Ke-Man Liao et al. · Advancement of science · 0 citations

Open access Sep 2026

Notoginsenoside R1 Attenuates Oxidative Damage After Intracerebral Hemorrhage by Inhibiting LCN2 and Promoting HO-1 in Astrocytes

Objectives: Intracerebral hemorrhage (ICH) is a devastating form of stroke characterized by high morbidity and mortality, but effective treatment strategy remains in urgent demand. Notoginsenoside R1 (NGR1), a bioactive component extracted from the traditional herb Panax notoginseng has been widely applied in the thera...

Qing-Yun Liu, Xiao Chen, Bao-Feng Wang et al. · Brain Science · 0 citations