Author

Bart Smeets

2 papers indexed here

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Preprint Aug 2026

Simulating is not always understanding: When model complexity obscures biology

In cell biology, computational models of biological systems range from minimal representations with a handful of parameters to whole-cell simulations tracking thousands of molecular species across a complete cell cycle. While these models span a continuum of detail, increasing complexity changes what they capture and a...

L. Gelens, Alejandro Fábregas-Tejeda, Grant Ramsey et al. · 0 citations

#diffusion models Open access Sep 2026

Matrix-controlled emergence of biofilm architecture shapes antimicrobial survival

Biofilms are structured microbial communities whose extracellular matrix is widely regarded as a basis of their protection against antimicrobial compounds. Yet how matrix production by individual bacteria gives rise to collective architecture and antimicrobial protection remains poorly understood. Here, we systematical...

Tom E. R. Belpaire, J. Meesters, Thibault Debord et al. · bioRxiv · 0 citations