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Bartłomiej Strzelec

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Open access Oct 2026

Is Aging a Failure to Resolve? Integrating Damage Responses, Regenerative Decline, and Geroscience Interventions

Biological aging is accompanied by persistent tissue-damage signaling, chronic inflammation, extracellular matrix remodeling, cellular senescence, and declining regenerative capacity. Taken together, these features resemble an injury response that is repeatedly initiated but fails to progress reliably through clearance...

P. Chmielewski, Bartłomiej Strzelec · 0 citations
Review Open access Sep 2026

The Hallmarks of Aging: From Molecular Mechanisms to Clinical Translation

This work evaluates the mechanistic and translational evidence for all twelve hallmarks of aging framework and examines RNA-processing defects and extracellular matrix remodeling as candidate processes without classifying either as an additional hallmark.

P. Chmielewski, Bartłomiej Strzelec · 0 citations

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