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Author

Basavaraju K. C.

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2 papers indexed here

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2026

Synergetic inhibition of deubiquitinases and acetyltransferases to regulate tau acetylation and aggregation in SH-SY5Y cell line model of Alzheimer's disease.

The development of standardized cell culture models in the SH-SY5Y neuronal system will be crucial to evaluating the therapeutic potential of this synergetic inhibition strategy, thereby restoring ubiquitination and promoting tau degradation.

Basavaraju K. C., Harshitha D. K., Poornima Priyadarshini · 0 citations
Review 2026

Bioenergetic impairment-induced Tau acetylation: Converging pathways in Alzheimer's disease.

Understanding the metabolic pathways that drive tau acetylation may offer new therapeutic targets aimed at restoring neuronal energy balance, re-establishing acetylation homeostasis, and potentially slowing the progression of AD.

Basavaraju K. C., Poornima Priyadarshini · 0 citations

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