In Vitro Antileishmanial Activity and Cytotoxicity Evaluation of 2-(Thiophen-2-ylmethyl)quinazolin-4(3H)-one Derivatives Against Leishmania tropica and Leishmania infantum
The molecular modeling findings suggest a potential interaction between E9 and trypanothione reductase, supporting the need for further evaluation of these compounds in intracellular amastigote models and subsequent in vivo studies and suggesting that the biological activity of this compound series may differ among Lei...