Neuromodulatory Regulation of Synaptic Transmission in the ARC AgRP→PVN Circuit Revealed by Optogenetics
Aim: This study aimed to investigate how dopamine, leptin, kappa opioid receptor signaling, and melanocortin receptors modulate synaptic transmission in the ARC AgRP→PVN pathway. Materials and Methods: We combined optogenetic stimulation with whole-cell electrophysiological recordings to directly assess synaptic streng...