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Author

Beatrix Ueberheide

2 papers indexed here

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Jul 2026

Noncanonical role for Caspase-5 in the human intestinal epithelium 2267092

Caspase-5 (CASP5) is a member of the inflammatory caspase family of cysteine proteases involved in inflammation and cell death. CASP5 shares highest homology with inflammatory caspase-4, but while caspase-4 is essential for noncanonical inflammasome activation, CASP5 is generally dispensable. This conundrum has l...

Yuhua Shi, Bao-Sen Jia, Yourae Hong et al. · 0 citations
Open access Jul 2026

Integrated Interactomics Reveals Novel Protein Associations: The FOXA1-PBX1 Complex as a Case Study

Protein-protein interactions (PPIs) are fundamental to cellular signaling networks, yet many remain undetected due to technical limitations of individual affinity purification approaches. To address this, we systematically mapped the interaction landscapes of six regulatory proteins involved in cell proliferation, immu...

Zhi Chen, Istvan Szepesi-Nagy, Qingyue Zhang et al. · 0 citations

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