Author

Ben J. Boyd

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Open access Aug 2026

Steric stabilizers inhibit or enhance enzymatic digestion depending on the internal nanostructure of lipid nanoparticles

Lipidic nanoparticles (LNPs), including liposomes and cubosomes, are widely employed drug delivery systems owing to their biocompatibility and capacity for stimuli-responsive ‘smart’ drug release. Steric stabilizers, including DSPE-PEG-2000 and Pluronic F127, are commonly used to stabilize LNPs by creating an effecti...

Jonathan Caukwell, Karl A. Hassan, Brett A. Neilan et al. · Interface Focus · 1 citation

Open access Aug 2026

Multiscale Characterization of Thermoresponsive Poly( N -vinylcaprolactam) Across Hydration States for Drug Delivery

Poly(N-vinylcaprolactam) (PNVCL) is a thermoresponsive polymer of particular interest for stimuli-responsive drug delivery due to its physiologically relevant lower critical solution temperature (LCST). However, temperature-induced conformational changes vary significantly with polymer concentration, making the polym...

Camilla Hald Gregersen, K. Be̅rziņš, J. Kirkensgaard et al. · ACS Applied Polymer Material... · 0 citations

Open access Jun 2026

Liquid crystalline mesophase spacing as a quantitative predictor of release kinetics for co-loaded hydrophilic and hydrophobic payloads

Synchrotron SAXS establishes characteristic repeat spacing as a quantitative structural metric directly governing hydrophilic release kinetics, providing a rational design framework linking mesophase architecture to functional performance across a range of payload structures.

S. R. Dasaro, Shruti S Sawant, Alexa Stern et al. · bioRxiv · 0 citations