Ben-Jun Yu

CPT1A as a metabolic gatekeeper linking fatty acid oxidation, ferroptosis resistance, and breast cancer stemness

Breast cancer stem-like cells sustain residual disease, metastatic recurrence and resistance to systemic and local therapies. Their defining metabolic feature is not a fixed preference for glycolysis or oxidative phosphorylation, but the capacity to reallocate substrates while preserving energy and redox homeostasis. C...