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Author

Bence Daniel

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Open access Sep 2026

Regulation of immune signal integration and memory by inflammation-induced chromosome conformation

Significance Innate immune cells integrate inflammatory cues and retain transcriptional memory, a phenomenon previously attributed mainly to one-dimensional epigenetic mechanisms. We show that inflammatory cytokine exposure remodels the three-dimensional (3D) genome of macrophages by establishing stable chromatin loops...

Bence Daniel, Andy Y. Chen, Katalin D. Sandor et al. · 1 citation

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