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Author

Benjamin Jones

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Preprint Aug 2026

PSLL: Persistent Sheaf Laplacian Learning for Protein-Ligand Binding Affinity Prediction

The computational results indicate that the proposed Persistent Sheaf Laplacian learning (PSLL) model achieves strong predictive performance across benchmark datasets, highlighting its potential as an interpretable and mathematically grounded framework with promising generalizability for molecular machine learning and...

Mushal Zia, Benjamin Jones, Guo-Wei Wei · 0 citations

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