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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

B. Schlechter

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2 papers indexed here

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Sep 2026

Abstract B096: Immune and stromal features of durable complete response to radiation and dual immune checkpoint blockade in pancreatic cancer

Microsatellite stable (MSS) pancreatic ductal adenocarcinoma (PDAC) is refractory to immune checkpoint blockade, reflecting an immunosuppressive stroma, impaired lymphocyte trafficking, and low neoantigen burden. We conducted a single-arm phase II trial (NCT04361162) combining nivolumab, ipilimumab and radiation ther...

Sarah Kang, M. Parikh, Leontios Pappas et al. · 0 citations
Open access Oct 2026

A Phase II Study of Nivolumab and Ipilimumab with Radiation Therapy in Patients with Metastatic, Microsatellite Stable Colorectal Cancer.

PURPOSE Immune checkpoint inhibitors (ICIs) have significantly altered the natural history of microsatellite instability high (MSI-H) colorectal cancer (mCRC). For microsatellite stable (MSS) refractory mCRC, ICIs recently demonstrated efficacy signals in patients without liver metastases. This study evaluated combined...

Leontios Pappas, J. Koenig, B. Yeap et al. · 0 citations

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