Open access
Sep 2026
Functional clustering within glioblastoma identifies a network-integrated subtype with improved survival.
BACKGROUND Glioblastoma (GBM) is traditionally viewed as disrupting brain network connectivity. Recent evidence of tumor-neuron synaptic interactions suggests gliomas may actively engage with the brain. We hypothesized that GBM tumors contain functionally distinct intratumoral subregions that differentially couple with...
Dan-Ting Zeng, A. Snyder, K. Park et al.
· Neuro-Oncology · 0 citations