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Benjamin T. James

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Open access Sep 2026

Cross-species single-cell atlas of the striatum defines cell-type and subregion disease vulnerabilities

Using single-nucleus RNA sequencing across 109 human and 22 mouse samples spanning dorsal and ventral striatum, a comprehensive atlas of subregional neuronal specialization is provided, suggesting divergent pharmacological targets, connectivity, and disease mechanisms.

Raleigh M. Linville, Benjamin T. James, K. Galani et al. · 2 citations · ⚡1
Open access Jul 2026

An encyclopedia of human enhancer–gene regulatory interactions

An encyclopedia of enhancer–gene regulatory interactions in the human genome is built, revealing global properties of enhancer networks, identifying differences in regulatory complexity across genes, and improving analyses linking noncoding variants to target genes and cell types for common, complex diseases.

A. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh et al. · 6 citations

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