Author

Benoit Blanchet

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Open access Sep 2026

From Clinical Trials to Real-World Patients: Population Pharmacokinetics and Precision Dosing Simulations of Lorlatinib.

Simulations suggest that lower lorlatinib doses may be feasible and MIPD may reduce toxicity, underscoring the importance of external validation of clinical trial-derived models.

L. Bukkems, Benoit Blanchet, J. Arrondeau et al. · Clinical Pharmacokinetics · 0 citations