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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Benoit Liquet

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Open access Sep 2026

Identity-by-descent to resolve reduced penetrance and advance gene discovery in neurodegenerative disease.

Advances in sequencing technologies have transformed human genetics and accelerated disease gene discovery. Yet a causal mutation remains to be identified for many families with an inherited disease. Incomplete penetrance, genetic heterogeneity, and limited family history can complicate the binary classification of fam...

L. Henden, Sandrine Chan Moi Fat, Andrew N. Smith et al. · 0 citations
Review Open access Aug 2026

A Guide for Exploring Pleiotropic Associations in Genome‐Wide Association Studies Using Summary Statistics

This tutorial reviews several widely used methods for pleiotropy detection from GWAS summary statistics, including ASSET, PLACO, GPA, CPBayes, and GCPBayes, and demonstrates their application using breast and thyroid cancer datasets.

Christina Y. Feng, P. Sugier, Nan Zou et al. · 0 citations

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