Aug 2026
6-aminonicotinamide dismantles proliferative and migratory capacities of oral cancer cells via PPP blockade.
OBJECTIVE Cancer cells frequently exploit the Pentose Phosphate Pathway (PPP) to fuel antioxidant defenses and the synthesis of essential biomolecular precursors. It is hypothesized that sustained upregulation of glucose flux through the PPP is crucial for meeting the anabolic demands of cancer cells and mitigating oxi...
L. Diel, S. E. C. de Mattos, Julia Stela Xavier Paim et al.
· Archives of Oral Biology · 0 citations