Established clinical MR imaging offers limited accuracy for the precise classification of adult-type diffuse glioma. The purpose of this study was to identify robust 7T MRSI metabolic markers that distinguish glioblastoma, IDH-wildtype (GBM); astrocytoma, IDH-mutant (AST) and oligodendroglioma, IDH-mutant, 1p/19q...
S. Huskić, P. Lazen, Thomas Roetzer-Pejrimovsky et al.· Cancer Imaging· 0 citations
This synthetic benchmark supports development and comparison of MRSI processing, nuisance-signal removal, and metabolite-quantification methods, while enabling method evaluation, and illustrates how characterized synthetic data can support rigorous evaluation when ground truth is difficult or impossible to obtain.
John LaMaster, J. Merkofer, Dennis M J van de Sande et al.· 0 citations
Dynamic deuterium metabolic imaging (DMI) enables time-resolved mapping of cerebral glucose metabolism in vivo, yet its intrinsically low SNR often renders voxel-wise metabolite quantification unstable-particularly at early repetitions. Low-rank denoising is widely used in MR spectroscopic imaging (MRSI)/DMI to improve...
Hauke Fischer, S. Motyka, Anna Duguid et al.· NeuroImage· 0 citations
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