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Author

Bernie Devlin

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Open access Aug 2026

Inferring disruption of directed graphs using LIKA reveals altered protein phosphorylation networks in schizophrenia

Motivation Kinases regulate a multitude of protein functions, and their dysregulation is pivotal for many human diseases. Direct measurement of kinase activity, however, is often challenging; therefore, inferring activity from the behavior of their substrates is a widely adopted strategy. Nonetheless, traditional metho...

Lujing Zhang, A. DeMarco, Kimia Ghafari et al. · 0 citations

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