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Bethany L. Hardman

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Open access Oct 2026

Tropolone and hinokitiol act against Staphylococcus aureus by concentration-dependent iron restriction or toxic iron overload

ABSTRACT Transition metal homeostasis is a critical component of bacterial physiology and thus represents a promising opportunity for antimicrobial intervention. Here, we demonstrate that the naturally occurring chelators tropolone (TRO) and hinokitiol (HNK) inhibit Staphylococcus aureus growth through concentration-de...

Bethany L. Hardman, Gary J. Sharples · 0 citations

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