Author

Bharath Reddy Boya

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Open access Aug 2026

Antifungal activity of the nucleoside mimetic 5-fluorouridine against Candidozyma auris and Candida species

5-fluorouridine is identified as a promising antifungal candidate and C-5-halogenated nucleosides are established as a privileged scaffold for antifungal drug development.

Bharath Reddy Boya, Ezhaveni Sathiyamoorthi, Jin-Hyung Lee et al. · Antimicrobial Agents and Che... · 0 citations

Jul 2026

Lauric Acid- and BDSF-Derived N-Acyl Sulfonamides as Potent Antibiofilm and Antivirulence Agents against Staphylococcus aureus.

Biofilm-associated Staphylococcus aureus infections remain difficult to treat using conventional antibiotics. Herein, we report the synthesis and biological evaluation of lauric acid- and BDSF-derived N-acyl sulfonamides as antibiofilm and antivirulence agents. Structure-activity relationship (SAR) analysis identified...

Yong-Guy Kim, Michelle O'Driscoll, Conor Horgan et al. · Journal of Medicinal Chemist... · 0 citations