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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Bhargav Shreevatsa

h-index 6 View on Semantic Scholar

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Review Open access Sep 2026

Silencing with precision: In silico strategies for antisense oligonucleotide engineering

Therapeutics based on nucleic acids are emerging as a transformative drug class in the era of personalized medicine. They include antisense oligonucleotides (ASOs), aptamers, small interfering RNAs (siRNAs), small activating RNAs (saRNAs), microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), in addition to messenger...

Abhigna Nagaraj, C. Kavana, Bhavana Harendra et al. · 0 citations
Open access Aug 2026

7-Deshydroxypyrogallin-4-carboxylic acid dietary phytochemical as a putative FTO inhibitor in breast cancer: an integrated computational and cytotoxicity study.

These findings provide a preliminary mechanistic and experimental framework for DCA as a dietary FTO inhibitor in breast cancer, necessitating further validation through orthogonal target engagement assays, m6A quantification, and in vivo tumor models.

Shuaib Pasha, S. Harishkumar, Revanth Handralu Chandraiah et al. · 0 citations

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