Dosimetric Impact of Deformable Image Registration versus Simple Summation in Multi-Fraction HDR Brachytherapy for Cervical Cancer under Standard Protocol
Objective: In high-dose-rate brachytherapy for cervical cancer, cumulative dose is commonly estimated using simple summation (SS) of dose–volume histogram parameters, assuming high-dose regions remain spatially consistent across fractions. Deformable image registration (DIR) offers an alternative approach that accounts...