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Author

Bhupesh Goyal

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Review Open access Aug 2026

Macrocyclic peptides and peptidomimetics as modulators of protein-protein interactions.

This review comprehensively examines the biological significance of PPIs in human disease and details how MPPs effectively modulate historically undruggable targets, highlighting current synthetic strategies, peptide engineering platforms, and the clinical and preclinical status of leading MPP candidates, while weighin...

Rajesh Parmar, Vidit Shrivastava, Gurmeet Kaur et al. · 0 citations
Aug 2026

Leveraging molecular dynamics to unravel the inhibition mechanism of potential β-secretase (BACE1) inhibitors.

The comprehensive in silico methodology in this work illuminated the inhibitory mechanism of LY3202626 and top hit compounds against BACE1 activity for the first time, which will be highly valuable in further optimization and structural refinement using various functional group modifications to yield more potent next-g...

Gurmeet Kaur, Bhupesh Goyal · 0 citations

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