Author

Bi-Bo Zhu

3 papers indexed here

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Sep 2026

The D389G mutation in E protein attenuates replication and virulence of Japanese encephalitis virus.

Japanese encephalitis virus (JEV) is a mosquito-borne Orthoflavivirus that causes reproductive disorders in pigs and severe neurological sequelae in humans. Although genotypes I (GI) and III (GIII) have been dominant worldwide, the recent emergence of GV in South Korea underscores the urgent need to identify cross-geno...

Sheng-Xian Xiang, Yi-Yang Shi, Cheng-Jie Yang et al. · Veterinary Microbiology · 0 citations

Open access Sep 2026

Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity

ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐est...

Chuanri Zeng, Xiaowei Nan, Ting Wang et al. · Journal of Extracellular Ves... · 0 citations

Sep 2026

A recombinant pseudorabies virus co-expressing G2b and G2c S1 broadens neutralizing antibody responses against PEDV variants and enhances pre-existing vaccine-induced antibody responses.

Porcine epidemic diarrhea virus (PEDV) G2c variants harbor substantial antigenic alterations that reduce the cross-neutralizing activity of antibodies induced by current vaccines and may contribute to vaccine failure in the field. To explore a vaccine candidate capable of broadening antibody responses against genetical...

Qi-Cong Pan, F. Yan, Shi-Qiang Liu et al. · International Journal of Bio... · 0 citations