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Bi-Kun Xiao

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Open access Oct 2026

Hexokinase-2 moonlights as a suppressor of STING-mediated innate immunity.

Metabolic enzymes are increasingly recognized for "moonlighting" functions beyond their primary metabolic roles. While such non-canonical activities are well characterized in cancer biology, their roles in innate immunity remain poorly defined. Here, we show that Hexokinase II (HK2), a rate-limiting enzyme of glycolysi...

Chu-Chu Zhang, Fang-Xu Li, Ming Gao et al. · 0 citations

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