Open access
Oct 2026
LGR6 couples maresin 1 signaling to glycolytic flux and protein lactylation for the rescue of diabetic cardiomyopathy
ABSTRACT Background Diabetic cardiomyopathy (DbCM) is driven by metabolic inflexibility and impaired mitochondrial clearance. While the pro‐resolving lipid mediator Maresin 1 (MaR1) shows therapeutic promise, its capacity to correct the underlying metabolic‐epigenetic disturbances in DbCM remains undefined. Materials D...
Bin Feng, Chao Chen, Lin Chen et al.
· Journal of Diabetes Investig... · 0 citations