Polystyrene Microplastics Exacerbate Arsenic-Induced Ferroptosis and Lipid Metabolism Dysregulation in Chicken Hepatocytes through SIRT7-SIRT1 Axis-Associated Transcriptomic Alterations
Co-contamination with arsenic (As) and polystyrene microplastics (PS-MPs) poses a significant risk to environmental health. This study elucidated the synergistic toxicity mechanism of PS-MPs and As using a chicken hepatocyte model, integrating electron microscopy, migration assays, and comprehensive biomarker assessm...