Open access
Oct 2026
Ibuprofen impairs fracture healing by disrupting neutrophil-mediated tissue repair
Neutrophils are among the first immune cells recruited to fractures, yet their contribution to bone repair remains poorly understood. Anti-inflammatory use has been linked to increased risk of non-union fractures, while prolonged neutrophil activity or failed clearance of neutrophil-derived DNA in the form of neutrophi...
J. Zappia, Lucy M. McGowan, Rebecca M. Chatwin et al.
· bioRxiv · 0 citations