Association of TLR-2 23 bp ins/del polymorphism (rs111200466) with susceptibility and clinical severity in ankylosing spondylitis: A hospital-based case-control study.
BACKGROUND Ankylosing spondylitis (AS) is an inflammatory disorder exacerbated by the innate immune response. A 23-bp ins/del polymorphism at the 5'-untranslated region of the TLR-2 gene (rs111200466) is linked to varying expression levels of inflammatory cytokines, crucial in AS pathogenesis. This study examined the a...