Jul 2026
Abstract B055: Targeting LSD1 for anti-PD1 therapy resistance mechanism in Head and Neck Cancer for future therapy
Head and Neck Squamous cell carcinoma (HNSCC) frequently exhibits resistance to anti–PD-1 immune checkpoint blockade. We asked whether dysregulated major histocompatibility complex class I (MHC-I) is a determinant of anti–PD-1 resistance, and whether targeting Lysine-specific demethylase 1 (LSD1/KDM1A) is an effe...
A. Chakraborty, R. Raut, Chumki Choudhury et al.
· Clinical Cancer Research · 0 citations