Bilgin Güngör

Aspiration-induced orthotopic lung cancer model: a non-invasive method for in vivo tumor microenvironment studies

Background Solid tumors account for the majority of cancer-associated morbidity, and the tumor microenvironment (TME) is a critical determinant of therapeutic response. However, the limited availability of optimized preclinical orthotopic cancer models that allow investigation of the TME constrains the development an...