Jul 2026
Design, synthesis, antimicrobial evaluation, and molecular dynamics-based computational investigation of novel imidazole-based FabI-targeted derivatives with antioxidant, DNA nicking, and cytotoxicity studies.
Overall, BS3 was identified as a potential lead compound for further optimization as an antimicrobial agent and demonstrated concentration-dependent cytotoxicity with acceptable cell viability at lower concentrations.
Bhargav Devliya, Bimalkumar Patel, Shreya J. Chauhan et al.
· Bioorganic chemistry (Print) · 1 citation