Open access
Sep 2026
Atherosclerotic Cardiovascular Diseases Increase ALS Risk by 82% While Optimal Cardiovascular Health Halves It: A 0.5-Million Prospective Cohort Study.
OBJECTIVE The objective of this study was to determine whether prevalent atherosclerotic cardiovascular diseases (ASCVDs) increase the risk of amyotrophic lateral sclerosis (ALS) and whether high cardiovascular health (CVH) can offset this risk. METHODS We prospectively analyzed 502,279 UK Biobank participants (37-73...
Jia-Li Xie, Hao-Bo Xie, Yao-Jia Li et al.
· Annals of Neurology · 0 citations