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Open access Jul 2026

Association of comorbidity burden with initial treatment allocation in older women with gynecologic cancer: a retrospective cohort study

The internally validated host-factor-oriented model may support individualized treatment discussions as an adjunct to multidisciplinary assessment, but it should not be interpreted as a tumor-specific treatment algorithm or as a replacement for disease-specific guideline-based decision-making.

Lin Tang, Yuhang Liu, Bin Chen et al. · 0 citations
Preprint Aug 2026

Double Machine Learning with High-dimensional Interactive Fixed Effects

The method combines projection-based defactorisation of the data, in the spirit of Common Correlated Effects, with a Neyman-orthogonal score function and cross-fitting procedure, and accommodates low-rank factor structures in outcomes and treatments alongside high-dimensional, potentially nonlinear covariate effects es...

Bin-Zhi Chen, Annalivia Polselli, P. Clarke · 0 citations

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