Author

Bin Hu

2 papers indexed here

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Open access Oct 2026

PathoEvo: an interactive single-cell database for exploring disease progression and pathological evolution.

Disease progression is driven by coordinated changes in tissue microenvironments, cellular composition, cell states, and transcriptional programmes. Single-cell and single-nucleus RNA sequencing enable these changes to be studied at cellular resolution. However, public disease-associated datasets are often organized wi...

Shuang Feng, Li-Fen Zhang, Shu-Xiang Yang et al. · Nucleic Acids Research · 0 citations

Open access Sep 2026

CryoFlex characterizes structural motion between conformations directly from cryo-EM density maps

Heterogeneous cryo-EM reconstruction methods can resolve multiple conformational states, but understanding their functional implications often requires determining which regions move between states and quantifying their displacement magnitudes. Comparing atomic models can quantify motion, but flexible regions are often...

Hao Dong, Fu-Wei Li, Yuan-Bo Chen et al. · bioRxiv · 0 citations