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Bin Tan

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Open access Aug 2026

SARS-CoV-2 Papain-Like Protease: Drug Design, Assay Development, and Drug Resistance.

This Account summarizes the group's effort to convert PLpro from a challenging target into a tractable antiviral drug-discovery platform and illustrates how integrated assay development, structural biology, medicinal chemistry, pharmacology, virology, and resistance analysis can transform a challenging viral deubiquitinase into a credible antiviral target.

Jun Wang, Kan Li, Bin Tan · 0 citations

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