Aug 2026
Ferroptosis drives LPS-induced injury in IPEC-J2 cells and is targeted by Rutin through NFE2L2, KEAP1, TLR4 and ALOX5.
Lipopolysaccharide (LPS)-induced intestinal epithelial injury contributes to the loss of gut homeostasis. Whether ferroptosis is involved in this injury and whether rutin can attenuate ferroptosis-associated changes in porcine intestinal epithelial cells remain unclear. In this in vitro study, IPEC-J2 cells were expose...
Lele Huo, Jun-Ying Liu, Mengxuan Li et al.
· Food and Chemical Toxicology · 0 citations