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Review Open access Sep 2026

Multi-target neuroprotective mechanisms of epigallocatechin-3-gallate (EGCG) in stroke: from molecular pathways to nanomedicine delivery and clinical translation

Stroke ranks among the leading global causes of mortality and permanent disability. Its secondary brain injury arises from multiple interrelated pathological cascades, including oxidative stress, neuroinflammation, disrupted autophagy-apoptosis balance, excitotoxicity, iron dyshomeostasis, and blood–brain barrier (BBB)...

Yi-Fan Yuan, Cui-Mei Xie, Ya-Ting Huang et al. · 0 citations
Review Open access Aug 2026

Neurotoxic mechanisms of cadmium in neurodegenerative diseases

Cadmium (Cd) is a highly toxic, bioaccumulative heavy metal increasingly implicated in the pathogenesis of neurodegenerative disorders. This review systemically characterizes the molecular mechanisms underlying Cd-induced neurotoxicity, with particular emphasis on oxidative stress-mediated pathways that initiate interc...

Zi-Hao Zhang, Yu-Tao Lu, Jia-Wei Yang et al. · 0 citations

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