Stroke ranks among the leading global causes of mortality and permanent disability. Its secondary brain injury arises from multiple interrelated pathological cascades, including oxidative stress, neuroinflammation, disrupted autophagy-apoptosis balance, excitotoxicity, iron dyshomeostasis, and blood–brain barrier (BBB)...
Yi-Fan Yuan, Cui-Mei Xie, Ya-Ting Huang et al.· Frontiers in Pharmacology· 0 citations
Cadmium (Cd) is a highly toxic, bioaccumulative heavy metal increasingly implicated in the pathogenesis of neurodegenerative disorders. This review systemically characterizes the molecular mechanisms underlying Cd-induced neurotoxicity, with particular emphasis on oxidative stress-mediated pathways that initiate interc...
Zi-Hao Zhang, Yu-Tao Lu, Jia-Wei Yang et al.· Frontiers in Cell and Develo...· 0 citations
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