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Author

Bing Guan

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Open access Oct 2026

Isolated TERT promoter mutation may define a high-risk prognostic subgroup in papillary thyroid carcinoma: an exploratory, hypothesis-generating analysis of TCGA and GSE33630 datasets

Background The prognostic value of combined BRAF V600E and TERT promoter (TERTp) mutations in papillary thyroid carcinoma (PTC) has been established in surgical cohorts. However, the independent impact of TERTp mutation in the absence of BRAF mutation remains underexplored, particularly within publicly available genomi...

Bing Guan, Rong Zhou, Si-Jia Zhang et al. · 0 citations
Meta-analysis Open access Oct 2026

PD-1/PD-L1 inhibitors combined with chemotherapy or as monotherapy versus chemotherapy alone or observation in triple-negative breast cancer: a systematic review and updated meta-analysis incorporating long-term survival data

Background Multiple RCTs have established PD-1/PD-L1 inhibitors as standard in triple-negative breast cancer (TNBC), but prior meta-analyses lacked complete setting coverage, mature long-term survival data, and a quantification of chemotherapy-backbone impact—critical given IMpassion130 (nab-paclitaxel, positive) vs. I...

Bing Guan, Ya-Wen Chen, Rong Zhou et al. · 0 citations

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