Author

Bingqi Zhu

4 papers indexed here

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Oct 2026

Study on the Intervention of Hirsutella sinensis Polysaccharides in Atopic Dermatitis via the NF-κB/MAPK and Nrf2/HO-1 Pathways: In Vitro and In Vivo Investigation.

THNOPHARMACOLOGICAL RELEVANCE Hirsutella sinensis is a well-known traditional medicinal fungus used in Chinese and Tibetan folk medicine for treating inflammatory and skin disorders. However, modern scientific evidence supporting its efficacy against atopic dermatitis (AD) remains insufficient, especially for its intra...

Shu-Shu Xie, Yu-Wan Wu, Jing-Wen Xu et al. · Journal of Ethnopharmacology · 0 citations

Sep 2026

Anti-inflammatory activity and structure-function analysis of degraded polysaccharide fragments from Tetrastigma hemsleyanum.

Tetrastigma hemsleyanum Diels et Gilg (T. hemsleyanum) is a medicinal plant with immunomodulatory activity. Its acidic glucuronic acid galactomannan (STHP5, 128 kDa) is degraded into fragments STHP5 DF-1 (78 kDa, helical, 2,3-Manp backbone, the main active fragment). STHP5 DF-1 inhibited NO and inflammatory cytokines,...

Ya-Fei Li, Kui-Xu Gao, Shuang-Yi Zhang et al. · International Journal of Bio... · 0 citations

Aug 2026

Tetrastigma hemsleyanum polysaccharides ameliorate inflammatory bowel disease via sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 -mediated gut vascular barrier repair.

It is demonstrated that THP alleviates IBD by repairing the GVB through the S1P/S1PR2 axis, providing a mechanistic basis for GVB-targeted therapeutic strategies.

Wenxuan Li, Yi-Wen Hu, Menghan Yang et al. · Phytomedicine · 0 citations

Open access Jul 2026

Colon-targeting pH-responsive Bletilla striata polysaccharide coacervate microdroplets for ulcerative colitis therapy via macrophage reprogramming

Ulcerative colitis (UC) is an immune-mediated chronic inflammatory bowel disease that severely impairs patients’ quality of life. Efficient oral colon-targeted delivery systems are urgently needed to improve local therapeutic efficacy while minimizing systemic exposure. Herein, we developed a pH-responsive Eudragit S10...

Qiantao Zhang, L. Chai, Hui Liu et al. · Journal of Nanobiotechnology · 0 citations