Open access
Sep 2026
RfaH licenses RNA polymerase for long-range transcription
RfaH, a NusG paralog recruited at ops and essential for long virulence operons, loads onto ops-paused RNAP by two pathways: one permitting immediate escape, the other requiring GreA rescue, which provides the foundation for dissecting virulence operon expression and its therapeutic targeting.
Luca Buccolieri, Bing Wang, Pim P. B. America et al.
· bioRxiv · 0 citations