: Coronary heart disease (CHD) remains a leading cause of global mortality, with unresolved inflammation constituting a major residual risk after conventional therapies. Macrophage polarization, characterized by shifts between pro-inflammatory M1 and reparative M2 phenotypes, influences vascular inflammation, plaque st...
Shuai Wang, Dong-Shuai Zhang, Yan-Dan Yang et al.· Journal of Inflammation Rese...· 0 citations
Atherosclerosis is a chronic inflammatory disease shaped by interactions among vascular cells, innate immunity, adaptive immunity, and metabolic stress. Interleukin-18 (IL-18), an IL-1 superfamily cytokine activated predominantly downstream of inflammasomes, links vascular injury to type 1 immune responses. This struct...
Dong-Shuai Zhang, Shuai Wang, Yang Li et al.· Frontiers in Cardiovascular...· 0 citations
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